Chronic Alcohol Ingestion and Predisposition to Lung “Cirrhosis”

Alcohol, Cirrhosis, and Genetic Predisposition

......................................... Received: 15-12-14 Accepted: 26-01-16 Abstract Liver cirrhosis is the third most common cause of death attributable to alcohol consumption throughout the world. More than 80% of chronic drinkers develop steatosis, and 20% to 40% develop other complications such as fibrosis, alcoholic hepatitis and cirrhosis. However, not everyone who chronically consume...

Effect of Chronic Alcohol Ingestion on Bone Mineral Density in Males without Liver Cirrhosis

BACKGROUND Osteoporosis in men is an important public health problem. Because of the tendency of the numbers of the elderly population to increase, and age-specific incidence of fractures, it is inevitable that the health burden due to fractures will increase. Chronic alcoholism is associated with other risk factors, such as poor nutrition, leanness, liver disease, malabsorption, vitamin D defi...

Chronic ingestion of alcohol modulates expression of ubiquitin editing enzyme A20 in lung macrophages

BACKGROUND Alcohol abuse is involved in the pathogenesis of multiple organ disorders; the underlying mechanism is incompletely understood. The ubiquitin editing enzyme A20 is involved in regulating activities in the cell. Suppression of A20 is suggested as one factor in the initiation of inflammation. This study investigates the mechanism by which chronic alcohol consumption modulates the level...

Chronic Alcohol Ingestion Changes the Landscape of the Alveolar Epithelium

Similar to effects of alcohol on the heart, liver, and brain, the effects of ethanol (EtOH) on lung injury are preventable. Unlike other vital organ systems, however, the lethal effects of alcohol on the lung are underappreciated, perhaps because there are no signs of overt pulmonary disorder until a secondary insult, such as a bacterial infection or injury, occurs in the lung. This paper provi...

Alcohol: effect on blood pressure and predisposition to hypertension.